The effects of amphotericin B on angiogenesis in chick chorioallantoic membrane
CUTANEOUS AND OCULAR TOXICOLOGY, vol.35, no.2, pp.92-96, 2016 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 35 Issue: 2
- Publication Date: 2016
- Doi Number: 10.3109/15569527.2015.1030756
- Journal Name: CUTANEOUS AND OCULAR TOXICOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.92-96
- Hacettepe University Affiliated: Yes
Abstract
Objective: Amphotericin B (AmB) is widely used as a mainstay in the treatment of sight-threatening fungal endophthalmitis. From the time that itraconazole was discovered to have a previously unknown anti-angiogenic activity, we have suspected that AmB may have possible effects on ocular angiogenesis. The purpose of this study was to evaluate the in vivo anti-angiogenic effect of AmB in the chick chorioallantoic membrane (CAM) model.