The effects of amphotericin B on angiogenesis in chick chorioallantoic membrane


Gokce G., Ozgurtas T., SOBACI G. , Kucukevcilioglu M.

CUTANEOUS AND OCULAR TOXICOLOGY, cilt.35, ss.92-96, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 35 Konu: 2
  • Basım Tarihi: 2016
  • Doi Numarası: 10.3109/15569527.2015.1030756
  • Dergi Adı: CUTANEOUS AND OCULAR TOXICOLOGY
  • Sayfa Sayıları: ss.92-96

Özet

Objective: Amphotericin B (AmB) is widely used as a mainstay in the treatment of sight-threatening fungal endophthalmitis. From the time that itraconazole was discovered to have a previously unknown anti-angiogenic activity, we have suspected that AmB may have possible effects on ocular angiogenesis. The purpose of this study was to evaluate the in vivo anti-angiogenic effect of AmB in the chick chorioallantoic membrane (CAM) model.