Preparation of well-defined erythromycin imprinted non-woven fabrics via radiation-induced RAFT-mediated grafting

Soylemez M., BARSBAY M., GUVEN O.

RADIATION PHYSICS AND CHEMISTRY, vol.142, pp.77-81, 2018 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 142
  • Publication Date: 2018
  • Doi Number: 10.1016/j.radphyschem.2017.01.041
  • Journal Name: RADIATION PHYSICS AND CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.77-81
  • Keywords: Molecularly imprinted polymers, Radiation induced grafting, RAFT polymerization, Erythromycin, TRANSFER PRECIPITATION POLYMERIZATION, PERFORMANCE LIQUID-CHROMATOGRAPHY, TANDEM MASS-SPECTROMETRY, SOLID-PHASE EXTRACTION, MACROLIDE ANTIBIOTICS, SUSPENSION POLYMERIZATION, POLYMERS, MICROSPHERES, ACID, SEPARATIONS
  • Hacettepe University Affiliated: Yes

Abstract

Radiation-induced RAFT polymerization technique was applied to synthesize well-defined molecularly imprinted polymers (MIPs) of erythromycin (ERY). Methacrylic acid (MAA) was grafted onto porous polyethylene (PE)/polypropylene (PP) nonwoven fabrics, under gamma-irradiation by employing 2-pheny-2-propyl benzodithioate as the RAFT agent and ethylene glycol dimethacrylate (EGDMA) as the crosslinker. MAA/erythromycin ratios of 2/1, 4/1, 6/1 were tested to optimize the synthesis of MIPs. The highest binding capacity was encountered at a MAA/ERY ratio of 4/1. Non-imprinted polymers (NIPs) were also synthesized in the absence of ERY. The MIPs synthesized by RAFT method presented a better binding capacity compared to those prepared by conventional method where no RAFT agent was employed.