Iridoid glycosides from Globularia davisiana

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Calis I., Kirmizibekmez H., Tasdemir D., Ireland C.

CHEMICAL & PHARMACEUTICAL BULLETIN, vol.50, no.5, pp.678-680, 2002 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 50 Issue: 5
  • Publication Date: 2002
  • Doi Number: 10.1248/cpb.50.678
  • Journal Name: CHEMICAL & PHARMACEUTICAL BULLETIN
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.678-680
  • Hacettepe University Affiliated: Yes

Abstract

From the ethanolic extract of the aerial parts of Globularia davisiana. a new iridoid glycoside, davisioside (1), was isolated. Davisioside (1) comprises a rare iridoid aglycone structure with a saturated double bond between C-3 and C-4. Nine known iridoid glycosides, asperuloside (2). alpinoside (3), geniposide (4), globularin (5), globularicisin (6), 10-O-benzoylcatalpol (7), lytanthosalin (8), melampyroside (9), agnuside (10), and three known phenylethanoid glycosides, verbascoside, isoacteoside and leucosceptoside A Acre also isolated and characterized. The structures of the isolates were established by spectroscopic methods (one-dimensional (1D)- and two-dimensional (2D)-NMR, MS).