Effect of perioperative aspirin use on hemorrhagic complications in elective craniotomy for brain tumors: results of a single-center, retrospective cohort study

Hanalioglu Ş., Sahin B., Sahin O. S., Kozan A., Ucer M., Cikla U., ...More

JOURNAL OF NEUROSURGERY, vol.132, no.5, pp.1529-1538, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 132 Issue: 5
  • Publication Date: 2020
  • Doi Number: 10.3171/2018.12.jns182483
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, EMBASE, MEDLINE
  • Page Numbers: pp.1529-1538
  • Keywords: aspirin, acetylsalicylic acid, hemorrhage, thromboembolism, brain tumor, craniotomy, vascular disorders, LOW-DOSE ASPIRIN, NONCARDIAC SURGERY, SPINAL SURGERY, BLOOD-LOSS, SUBDURAL-HEMATOMA, TASK-FORCE, ANTIPLATELET, MANAGEMENT, THERAPY, ANTICOAGULANT
  • Hacettepe University Affiliated: Yes


OBJECTIVE In daily practice, neurosurgeons face increasing numbers of patients using aspirin (acetylsalicylic acid, ASA). While many of these patients discontinue ASA 7-10 days prior to elective intracranial surgery, there are limited data to support whether or not perioperative ASA use heightens the risk of hemorrhagic complications. In this study the authors retrospectively evaluated the safety of perioperative ASA use in patients undergoing craniotomy for brain tumors in the largest elective cranial surgery cohort reported to date.