Scintigraphic evaluation of the osteoblastic activity of rabbit tibial defects after HYAFF11 membrane application

Mermerkaya, Musa; DORAL, MAHMUT; Karaaslan, Fatih; HURİ, GAZİ; KARAÇAVUŞ, SEYHAN; KAYMAZ, BURAK; Alkan, Erkan

doi:10.1186/s13018-016-0393-y

Scintigraphic evaluation of the osteoblastic activity of rabbit tibial defects after HYAFF11 membrane application

Mermerkaya M. U., DORAL M. N., Karaaslan F., HURİ G., KARAÇAVUŞ S., KAYMAZ B., ...Daha Fazla

JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH, cilt.11, 2016 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 11
Basım Tarihi: 2016
Doi Numarası: 10.1186/s13018-016-0393-y
Dergi Adı: JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Hacettepe Üniversitesi Adresli: Evet

Özet

Background: An unfavorable condition for bone healing is the presence of bone defects. Under such conditions, a material can play a role to cover fractured or defective bone. Technological advances now allow for the use of such material. Hyalonect (R) (Fidia Advanced Biopolymers SLR, Italy), a novel membrane comprising knitted fibers of esterified hyaluronan (HYAFF11) can be used to cover fractured or grafted bone and can also serve as a scaffold to keep osteoprogenitor cells in place. The aim of this study was to compare osteoblastic activity by the use of scintigraphic methods in defective rabbit tibias during early-phase bone healing with or without a hyaluronan-based mesh.