Scintigraphic evaluation of the osteoblastic activity of rabbit tibial defects after HYAFF11 membrane application

Mermerkaya M. U., DORAL M. N., Karaaslan F., HURİ G., KARAÇAVUŞ S., KAYMAZ B., ...More

JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH, vol.11, 2016 (SCI-Expanded) identifier identifier identifier


Background: An unfavorable condition for bone healing is the presence of bone defects. Under such conditions, a material can play a role to cover fractured or defective bone. Technological advances now allow for the use of such material. Hyalonect (R) (Fidia Advanced Biopolymers SLR, Italy), a novel membrane comprising knitted fibers of esterified hyaluronan (HYAFF11) can be used to cover fractured or grafted bone and can also serve as a scaffold to keep osteoprogenitor cells in place. The aim of this study was to compare osteoblastic activity by the use of scintigraphic methods in defective rabbit tibias during early-phase bone healing with or without a hyaluronan-based mesh.