Scintigraphic evaluation of the osteoblastic activity of rabbit tibial defects after HYAFF11 membrane application

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Atıf İçin Kopyala

Mermerkaya M. U., DORAL M. N., Karaaslan F., HURİ G., KARAÇAVUŞ S., KAYMAZ B., ...Daha Fazla

JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH, cilt.11, 2016 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 11
• Basım Tarihi: 2016
• Doi Numarası: 10.1186/s13018-016-0393-y
• Dergi Adı: JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Hacettepe Üniversitesi Adresli: Evet

Özet

Background: An unfavorable condition for bone healing is the presence of bone defects. Under such conditions, a material can play a role to cover fractured or defective bone. Technological advances now allow for the use of such material. Hyalonect (R) (Fidia Advanced Biopolymers SLR, Italy), a novel membrane comprising knitted fibers of esterified hyaluronan (HYAFF11) can be used to cover fractured or grafted bone and can also serve as a scaffold to keep osteoprogenitor cells in place. The aim of this study was to compare osteoblastic activity by the use of scintigraphic methods in defective rabbit tibias during early-phase bone healing with or without a hyaluronan-based mesh.