Imaging features of CNS involvement in AIDS

SENOCAK E., Oguz K. K., OZGEN B., Kurne A., OZKAYA G., ÜNAL S., ...More

DIAGNOSTIC AND INTERVENTIONAL RADIOLOGY, vol.16, no.3, pp.193-200, 2010 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 3
  • Publication Date: 2010
  • Doi Number: 10.4261/1305-3825.018.2182-08.1
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.193-200
  • Keywords: acquired immunodeficiency syndrome, magnetic resonance imaging, central nervous system infections, lymphoma, ACQUIRED-IMMUNODEFICIENCY-SYNDROME, CENTRAL-NERVOUS-SYSTEM, PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY, HIV, INFECTIONS, SPECTRUM, PATIENT, CT
  • Hacettepe University Affiliated: Yes


Patients with acquired immunodeficiency syndrome (AIDS) are the subjects of a large part of routine neuroradiological work in the Western world currently. The World Health Organization announced that Turkish authorities had reported a cumulative total of 2544 HIV cases from 1985 to 2006, of whom 623 had developed AIDS and 140 had died. It is estimated that approximately one-third of AIDS patients develop neurological complications. The spectrum of diseases affecting the central nervous system (CNS) in AIDS patients comprises predominantly opportunistic infections and primary CNS lymphoma. Although to a lesser degree when compared with Western countries, the incidence of AIDS and related neurological diseases are on the rise also in Turkey. Therefore radiologists should recognize HIV-associated problems and their imaging features. In this review, we focus on imaging features of more common CNS diseases in HIV-seropositive patients. This essay has been prepared using radiological studies of the patients who had been managed in our hospital which is a tertiary care center with a highly motivated medical team for this peculiar disease in the years between 2002 and 2008.