Monitoring Achilles enthesitis in ankylosing spondylitis during TNF-alpha antagonist therapy: an ultrasound study

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Aydin S. Z., KARADAĞ Ö., Filippucci E., Atagunduz P., AKDOĞAN A., KALYONCU U., ...More

RHEUMATOLOGY, vol.49, no.3, pp.578-582, 2010 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 3
  • Publication Date: 2010
  • Doi Number: 10.1093/rheumatology/kep410
  • Journal Name: RHEUMATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.578-582
  • Keywords: Ultrasonography, Enthesitis, Achilles tendon, Ankylosing spondylitis, TNF-alpha antagonist therapy, POWER DOPPLER SONOGRAPHY, RHEUMATOID-ARTHRITIS, MUSCULOSKELETAL ULTRASOUND, CLINICAL MEASUREMENT, LOWER-LIMB, SPONDYLARTHROPATHY, ULTRASONOGRAPHY, SPONDYLOARTHROPATHY, ABNORMALITIES, ENTHESOPATHY
  • Hacettepe University Affiliated: Yes

Abstract

Objective. Enthesitis is considered as the primary anatomical lesion in ankylosing spondylitis (AS). Therapeutic effects of TNF-alpha antagonist treatments for enthesitis on imaging changes are still limited to case reports or small sample-sized trials. We aimed to investigate the potential of ultrasonography (US) to detect early changes after TNF-alpha antagonist therapy of Achilles enthesis of AS patients.