CYP2C19 genotype does not represent a genetic predisposition in idiopathic systemic lupus erythematosus


Kortunay S., Bozkurt A., Bathum L., Basci N. E. , Calguneri M., Brosen K., ...Daha Fazla

ANNALS OF THE RHEUMATIC DISEASES, cilt.58, ss.182-185, 1999 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 58 Konu: 3
  • Basım Tarihi: 1999
  • Doi Numarası: 10.1136/ard.58.3.182
  • Dergi Adı: ANNALS OF THE RHEUMATIC DISEASES
  • Sayfa Sayıları: ss.182-185

Özet

Background-The aetiology of systemic lupus erythematosus (SLE) is still unknown. In several cases, however, chemicals or drugs were identified as aetiological agents and associations with certain phenotypes of drug metabolising enzymes have been reported. The purpose of this study was to discover if there is an association between CYP2C19 polymorphism and susceptibility to SLE.