CYP2C19 genotype does not represent a genetic predisposition in idiopathic systemic lupus erythematosus

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Kortunay S., Bozkurt A., Bathum L., Basci N. E., Calguneri M., Brosen K., ...More

ANNALS OF THE RHEUMATIC DISEASES, vol.58, no.3, pp.182-185, 1999 (SCI-Expanded, Scopus)

• Publication Type: Article / Article
• Volume: 58 Issue: 3
• Publication Date: 1999
• Doi Number: 10.1136/ard.58.3.182
• Journal Name: ANNALS OF THE RHEUMATIC DISEASES
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.182-185
• Open Archive Collection: AVESIS Open Access Collection
• Hacettepe University Affiliated: Yes

Abstract

Background-The aetiology of systemic lupus erythematosus (SLE) is still unknown. In several cases, however, chemicals or drugs were identified as aetiological agents and associations with certain phenotypes of drug metabolising enzymes have been reported. The purpose of this study was to discover if there is an association between CYP2C19 polymorphism and susceptibility to SLE.