Increased ferritin levels could reflect ongoing aging-associated inflammation and may obscure underlying iron deficiency in the geriatric population

Cankurtaran, M.; Yavuz, B.; Halil, M.; Ulger, Z.; Haznedaroglu, I.; Ariogul, S.

doi:10.1016/j.eurger.2012.06.005

Increased ferritin levels could reflect ongoing aging-associated inflammation and may obscure underlying iron deficiency in the geriatric population

Atıf İçin Kopyala

Cankurtaran M., Yavuz B. B., Halil M., Ulger Z., Haznedaroglu I. C., Ariogul S.

EUROPEAN GERIATRIC MEDICINE, cilt.3, sa.5, ss.277-280, 2012 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 3 Sayı: 5
Basım Tarihi: 2012
Doi Numarası: 10.1016/j.eurger.2012.06.005
Dergi Adı: EUROPEAN GERIATRIC MEDICINE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.277-280
Hacettepe Üniversitesi Adresli: Evet

Özet

Background and aim: Ferritin level is decreased in iron deficiency (ID) and increased in inflammation as an acute-phase reacting protein. In the case of inflammation ferritin, level may not decrease even if ID is present. Inflammation is regarded as one of the mechanisms of aging. This subclinical systemic inflammatory state is named as "inflammaging". The aim of this study is to assess whether serum ferritin levels could indicate aging-associated inflammation rather than ID in older adults.