Alteration of enzyme activities and kinetic properties of GST and NQO1 with naturally occurring phenolic compounds

Karakurt S., Sever M., Celebioglu H. U., ADALI O.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.40, no.3, pp.251-257, 2015 (SCI-Expanded) identifier identifier


Objective: Glutathione S-transferase (GST) and NAD(P)H:quinine oxidoreductase 1 (NQO1) are the enzymes important in cytoprotection and bioactivation of chemicals. This study has addressed effects of polyphenolic compounds; ellagic acid, quercetin, naringenin, resveratrol, rutin and hesperidin on rabbit liver GST and NQO1 enzyme activities.