Neutrophil Formylpeptide Receptor Single Nucleotide Polymorphism 348T > C in Aggressive Periodontitis

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Maney P., Emecen P., Mills J. S., Walters J. D.

JOURNAL OF PERIODONTOLOGY, cilt.80, sa.3, ss.492-498, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 80 Sayı: 3
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1902/jop.2009.080225
  • Dergi Adı: JOURNAL OF PERIODONTOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.492-498
  • Hacettepe Üniversitesi Adresli: Hayır

Özet

Background: Neutrophil formylpeptide receptors (FPRs) play an important role in bacterial recognition and chemotaxis. Defective FPR1 expression and impaired polymorphonuclear leukocyte chemotaxis toward bacterial formylpeptides are associated with aggressive periodontitis (AgP). The objective of this study was to determine whether single nucleotide polymorphisms (SNPs) in FPR1 are associated with AgP.