Accuracy and effectiveness of HPV mRNA testing in cervical cancer screening: a systematic review and meta-analysis

---

Copy For Citation

Arbyn M., Simon M., de Sanjose S., Clarke M. A., Poljak M., Rezhake R., ...More

LANCET ONCOLOGY, vol.23, no.7, pp.950-960, 2022 (SCI-Expanded)

• Publication Type: Article / Review
• Volume: 23 Issue: 7
• Publication Date: 2022
• Doi Number: 10.1016/s1470-2045(22)00294-7
• Journal Name: LANCET ONCOLOGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, MEDLINE
• Page Numbers: pp.950-960
• Hacettepe University Affiliated: Yes

Abstract

Background Cervical cancer screening tests that identify DNA of the main causal agent, high-risk human papillomavirus (HPV) types, are more protective than cervical cytology. We systematically reviewed the literature to assess whether tests targeting high-risk HPV (hrHPV) mRNA are as accurate and effective as HPV DNA-based screening tests.