Prognostic significance of whole blood viscosity estimated by de Simone's formula in ST-elevation myocardial infarction

Cetin E. H. O. , Cetin M. S. , CANPOLAT U. , Aydin S., Aras D., Topaloglu S., ...Daha Fazla

BIOMARKERS IN MEDICINE, cilt.10, ss.495-511, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 10 Konu: 5
  • Basım Tarihi: 2016
  • Doi Numarası: 10.2217/bmm.16.10
  • Sayfa Sayıları: ss.495-511


Background: We assessed the predictive value of estimated whole blood viscosity (WBV) in-hospital and long-term cardiovascular outcomes in patients with ST-elevation myocardial infarction (STEMI). Materials & methods: One thousand eight hundred and thirty-five STEMI patients were followed up for median 34.6 months. WBV was calculated consistent with the de Simone's formula. Results: In-hospital and long-term major adverse cardiovascular events (MACE) demonstrated an incremental trend in ascending order of WBV tertiles at low and high shear rate. Kaplan-Meier analysis showed a higher occurrence of long-term MACE in third WBV tertiles compared with other tertiles. Conclusion: WBV seems to be a feasible prognostic indicator of short-and long-term cardiovascular adverse events in patients with STEMI. As an easily available parameter, WBV may be utilized in identifying high-risk patients for subsequent MACE.