Akademik Veri Yönetim Sistemi
TURKIYE KLINIKLERI TIP BILIMLERI DERGISI, cilt.29, sa.4, ss.1032-1034, 2009 (SCI-Expanded)
Generalized lymphadenopathy is defined as enlargement of more than two noncontiguous lymph node groups. Sometimes it can be a real diagnostic challenge to the physician because the associated diseases clinically and pathologically may mimic each other. The differential diagnosis is important because each cause necessitates a different therapeutic approach. Associated diseases include infections, malignancies, autoimmune diseases, benign hyperplasia, storage diseases, and drug reactions. Here we presented a patient who developed fever and lymphadeopathy after phenytoin use but whose clinical presentation was later found to be secondary to Epstein-Barr virus (EBV) infection. We discussed the differential diagnosis between drug reaction and EBV infection as a cause of generalized lymphadenopathy.