Sedative, anticonvulsant and behaviour modifying effects of Centranthus longiflorus ssp longiflorus: a study of comparison to diazepam

BUYUKOKUROGLU M., Demirezer L. Ö., GUVENALP Z.

PHARMAZIE, vol.57, no.8, pp.559-561, 2002 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 57 Issue: 8
  • Publication Date: 2002
  • Journal Name: PHARMAZIE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.559-561
  • Hacettepe University Affiliated: Yes

Abstract

The aqueous extract of Centranthus longiflorus ssp. longiflorus (CLE) was investigated for sedative, anticonvulsant and behaviour modifying activity using thiopental sleeping, caffeine induced convulsion and forced swimming depression tests. When the effects of the aqueous extract of CLE (100 mg/kg) was compared to diazepam, it showed similar sedative and anticonvulsant effects to those produced by diazepam (5 mg/kg).