Assessment of LXR alpha agonist activity and selective antiproliferative efficacy: a study on different parts of Digitalis species

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Atıf İçin Kopyala

KUTLUAY V. M., Inoue M., SARAÇOĞLU İ.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.44, sa.6, ss.745-751, 2019 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 44 Sayı: 6
• Basım Tarihi: 2019
• Doi Numarası: 10.1515/tjb-2018-0280
• Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
• Sayfa Sayıları: ss.745-751
• Hacettepe Üniversitesi Adresli: Evet

Özet

Objective: Aerial parts and roots of three Digitalis species (Digitalis davisiana Heywood, Digitalis viridiflora Lindley and Digitalis grandiflora Miller; Plantaginaceae) were investigated from the viewpoint of cytotoxicity to identify the biologically active parts. Playing a role in cell proliferation and tumor growth, LXR alpha agonist activity also has become of interest to researchers investigating its relationship with the cytotoxicity.