Soluble guanylyl cyclase activators increase the expression of tolerance to morphine analgesic effect

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Durmus N., Bagcivan I., Ozdemir E., ALTUN A., Gursoy S.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.115, no.6, pp.334-339, 2014 (SCI-Expanded) identifier identifier identifier


Objectives: It is aimed to investigate the effects of guanylyl cyclase activation and inhibition on acute morphine antinociception and the development of tolerance to its effect.