JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI, vol.84, no.4, pp.472-481, 2021 (Peer-Reviewed Journal)
Article / Article
JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI
Emerging Sources Citation Index, TR DİZİN (ULAKBİM)
Atherosclerosis, TIMP3, gene expression level, coronary artery, adipocyte, leukocyte, EPICARDIAL ADIPOSE-TISSUE, INSULIN-RESISTANCE, INFLAMMATION, DISEASE, OVEREXPRESSION, PROGRESSION, FAT
Objective: Tissue Inhibitor of Metalloproteinase-3 human (TIMP3) is one of tissue inhibitors of metalloproteinases (TIMPs), which binds to the components of the extracellular matrix, and has cru-cial roles in atherosclerogenesis and adipose tissue differentiation. In this study, it was aimed to determine the effects of TIMP3 gene expression levels on severity of atherosclerosis in different tissues.