PREPARATION OF MAGNETIC CHITOSAN NANOPARTICLES FOR DIVERSE BIOMEDICAL APPLICATIONS


Kavaz D., Cirak T., ÖZTÜRK E., BAYRAM C., DENKBAŞ E. B.

NATO Advanced Study Institute on Functionalized Nanoscale Materials, Devices and Systems for Chem-Bio Sensors, Photonics and Energy Generation and Storage, Sinaia, Romania, 4 - 15 June 2007, pp.313-320 identifier

  • Publication Type: Conference Paper / Full Text
  • Doi Number: 10.1007/978-1-4020-8903-9_23
  • City: Sinaia
  • Country: Romania
  • Page Numbers: pp.313-320
  • Keywords: Chitosan, magnetic nanoparticles, biotechnology, tripolyphosphate, ESR, VSM, ADSORPTION

Abstract

Polymeric nanoparticles with magnetic properties call be potentially used in many fields Such as biotechnology, separation processes, optoelectronic, catalysts and/or sensors, medical diagnosis and therapy. Ill this respect, biopolymers give promising trends due to their excellent biocompatibility and biodegradability. Therefore ill this Study, magnetic chitosan/Fe3O4 nanoparticles were prepared according to the procedure based oil the ionic gelation of chitosan with tripolyphosphate anions. The formation of the particles was a result Of the interaction between the negatively charged groups of the tripolyphosphate and the positively charged amino groups of chitosan. The prepared samples were observed by atomic force microscopy to obtain information about the morphology. The mean particle size of the nanoparticles was determined by dynamic light scattering measurements. Nanoparticles were spherical ill shape with a particle size range of about 250-400 nm according to obtained data. Magnetic properties of the nanoparticles were determined by using ESR and VSM.