Synthesis and antimicrobial activity of some new thiazolyl thiazolidine-2,4-dione derivatives

Bozdag-Duendar O., Oezgen O., Mentese A., Altanlar N., Atli O., Kendi E., ...More

BIOORGANIC & MEDICINAL CHEMISTRY, vol.15, no.18, pp.6012-6017, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 18
  • Publication Date: 2007
  • Doi Number: 10.1016/j.bmc.2007.06.049
  • Journal Name: BIOORGANIC & MEDICINAL CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.6012-6017
  • Hacettepe University Affiliated: No

Abstract

In this study, a series of thiazolyl thiazolidine-2,4-dione derivatives (Va-f and Vla-f) were synthesized and evaluated for their antibacterial and antifungal activities against Staphylococcus aureus (ATCC 25923), methicillin resistant S. aureus (MRSA ATCC 43300), methicillin resistant S. aureus (MRSA isolate), and Escherichia coli (ATCC 23556) and C. albicans (ATCC10145). All the compounds were found active against used microorganisms. (c) 2007 Elsevier Ltd. All rights reserved.