Synthesis and antimicrobial activity of some new thiazolyl thiazolidine-2,4-dione derivatives

Bozdag-Duendar O., Oezgen O., Mentese A., Altanlar N., Atli O., Kendi E., ...More

BIOORGANIC & MEDICINAL CHEMISTRY, vol.15, no.18, pp.6012-6017, 2007 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 18
  • Publication Date: 2007
  • Doi Number: 10.1016/j.bmc.2007.06.049
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.6012-6017


In this study, a series of thiazolyl thiazolidine-2,4-dione derivatives (Va-f and Vla-f) were synthesized and evaluated for their antibacterial and antifungal activities against Staphylococcus aureus (ATCC 25923), methicillin resistant S. aureus (MRSA ATCC 43300), methicillin resistant S. aureus (MRSA isolate), and Escherichia coli (ATCC 23556) and C. albicans (ATCC10145). All the compounds were found active against used microorganisms. (c) 2007 Elsevier Ltd. All rights reserved.