Novel multi-targeted agents for Alzheimer's disease: Synthesis, biological evaluation, and molecular modeling of novel 2-[4-(4-substitutedpiperazin-1-yl)phenyl]benzimidazoles


Ozadali-Sari K., Tüylü Küçükkılınç T., AYAZGÖK B., BALKAN A., Unsal-Tan O.

Bioorganic Chemistry, vol.72, pp.208-214, 2017 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 72
  • Publication Date: 2017
  • Doi Number: 10.1016/j.bioorg.2017.04.018
  • Journal Name: Bioorganic Chemistry
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.208-214
  • Keywords: Benzimidazole, Alzheimer's disease, Butyrylcholinesterase, A beta aggregation, Neuroprotection, TARGET-DIRECTED LIGANDS, AMYLOID-BETA PEPTIDE, BENZIMIDAZOLE DERIVATIVES, CHOLINERGIC HYPOTHESIS, THERAPEUTIC STRATEGIES, BUTYRYLCHOLINESTERASE, ACETYLCHOLINESTERASE, INHIBITORS, BRAIN, RIFAMPICIN
  • Hacettepe University Affiliated: Yes