Micelle-engineered nanoplatforms for precision oncology

Gao W., Bigham A., Ghomi M., ZARRABİ A., Rabiee N., Saeb M. R., ...More

CHEMICAL ENGINEERING JOURNAL, vol.495, 2024 (SCI-Expanded, Scopus) identifier identifier

  • Publication Type: Article / Review
  • Volume: 495
  • Publication Date: 2024
  • Doi Number: 10.1016/j.cej.2024.153438
  • Journal Name: CHEMICAL ENGINEERING JOURNAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Aerospace Database, Aqualine, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, Chimica, Compendex, Food Science & Technology Abstracts, INSPEC, Pollution Abstracts, Veterinary Science Database, Civil Engineering Abstracts
  • Hacettepe University Affiliated: Yes

Abstract

The alliance between nanomaterials and cancer therapy has revolutionized the treatment of tumor patients. After cardiovascular diseases, cancer is the leading cause of death, so interdisciplinary approaches should be used for the treatment of this malignant disease. Both treatment and early diagnosis of cancer are challenging. The micelles belong to lipid-based nanostructures, and they have a hydrophobic core with hydrophilic head regions. The current review article focuses on the application of micelles in cancer suppression. The micelles can provide a platform for co-delivery of non-coding RNAs and RNAi in cancer gene therapy. Both synthetic and natural