Akademik Veri Yönetim Sistemi
Hacettepe University Journal of the Faculty of Pharmacy, cilt.40, sa.2, ss.83-92, 2020 (Scopus)
The use of phytochemicals and herbs is as ancient as human due to their therapeutic effects, and then the effective, safety and inexpensive properties are the main reasons of their usage. Phytochemicals have beneficial effects against different diseases including autoimmune disorders. Immune system provides the protection of human body from pathogens like bacteria, virus, and fungi. Therefore, a breakdown in immune system often causes infections, diseases and autoimmune disorders. When immune system recognizes healthy cells as foreign cells and attacks them, an immune disorder can develop. Autoimmune disorders are identified as a specific adaptive immune response mounted against a self-antigen. They are chronic, life-threatening diseases of which the therapy is often impossible. Multiple sclerosis, rheumatoid arthritis, type 1 diabetes, inflammatory bowel disease, thyroiditis, uveitis, systemic lupus erythematosus, and myasthenia gravis are some of the known autoimmune disorders. This review aims to provide information about the use of phytochemicals against different autoimmune diseases by affecting the immune system.