Platelet lysate: a promising candidate in regenerative medicine

Meftahpour V., Malekghasemi S., Baghbanzadeh A., Aghebati-Maleki A., Pourakbari R., Fotouhi A., ...Daha Fazla

REGENERATIVE MEDICINE, cilt.16, ss.71-85, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 16
  • Basım Tarihi: 2021
  • Doi Numarası: 10.2217/rme-2020-0065
  • Dergi Adı: REGENERATIVE MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Chemical Abstracts Core, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.71-85
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Human platelet lysate has attracted much interest from many researchers as it is growth-factor rich for cell expansion, which is employed as a new therapeutic strategy. Not only are human platelet lysates used for cell therapy, but they are also used for the completion of basal media in mesenchymal stem cell cultures. Due to the presence of a large number of growth factors, platelet lysates have potential roles in wound healing, treatment of ocular graft-versus-host disease, osteoarthritis, Parkinson's disease, tendon regeneration, infertility, androgenetic alopecia, nerve repair and regenerative tissue, such as bone regeneration. In this review, we summarize that platelet lysates could be valuable candidates for the treatment of a variety of diseases in regenerative medicine.