Supporting Roles of Platelet Thrombospondin-1 and CD36 in Thrombus Formation on Collagen

Kuijpers, Marijke; de Witt, Susanne; Nergiz-Unal, REYHAN; van Kruchten, Roger; Korporaal, Suzanne; Verhamme, Peter; Febbraio, Maria; Tjwa, Marc; Voshol, Peter; Hoylaerts, Marc; Cosemans, Judith; Heemskerk, Johan

doi:10.1161/atvbaha.113.302917

Supporting Roles of Platelet Thrombospondin-1 and CD36 in Thrombus Formation on Collagen

Kuijpers M. J. E., de Witt S., Nergiz-Unal R., van Kruchten R., Korporaal S. J. A., Verhamme P., ...Daha Fazla

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, cilt.34, sa.6, ss.1187-1192, 2014 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 34 Sayı: 6
Basım Tarihi: 2014
Doi Numarası: 10.1161/atvbaha.113.302917
Dergi Adı: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1187-1192
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Hacettepe Üniversitesi Adresli: Evet

Özet

Objective Platelets abundantly express the membrane receptor CD36 and store its ligand thrombospondin-1 (TSP1) in the -granules. We investigated whether released TSP1 can support platelet adhesion and thrombus formation via interaction with CD36.