Supporting Roles of Platelet Thrombospondin-1 and CD36 in Thrombus Formation on Collagen

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Kuijpers M. J. E., de Witt S., Nergiz-Unal R., van Kruchten R., Korporaal S. J. A., Verhamme P., ...More

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, vol.34, no.6, pp.1187-1192, 2014 (SCI-Expanded) identifier identifier identifier


Objective Platelets abundantly express the membrane receptor CD36 and store its ligand thrombospondin-1 (TSP1) in the -granules. We investigated whether released TSP1 can support platelet adhesion and thrombus formation via interaction with CD36.