Multimodal Imaging for Subacute Sclerosing Panencephalitis: Including Anterior Segment
OPHTHALMIC SURGERY LASERS & IMAGING RETINA, vol.55, no.6, pp.344-348, 2024 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 55 Issue: 6
- Publication Date: 2024
- Doi Number: 10.3928/23258160-20240205-01
- Journal Name: OPHTHALMIC SURGERY LASERS & IMAGING RETINA
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, MEDLINE
- Page Numbers: pp.344-348
- Hacettepe University Affiliated: Yes
Abstract
Subacute sclerosing panencephalitis (SSPE) is an irreversible and progressive neurological disorder. A 20 -year -old woman with SSPE presented with a decline in visual acuity. Anterior segment was evaluated with slit lamp and in vivo confocal microscopy, revealing the presence of dendritiform keratic precipitates and +2 cells in the anterior chamber. In fundus examination, white -yellowish lesions involving the macula and periphery were observed, which gradually progressed into atrophy over time. Optical coherence tomography (OCT) imaging showed progression to atrophy of moth-eaten shaped cavities including all retinal layers due to necrotizing retinitis. OCT angiography (OCTA) further revealed reduced vessel densities and flow void areas. Notably, to the best of our knowledge, this is the first case documenting anterior segment findings in SSPE in detail.