MEFV mutations in systemic onset juvenile idiopathic arthritis


Ayaz N. A. , ÖZEN S. , BİLGİNER Y. , Erguven M., Taskiran E. , YILMAZ E. , ...Daha Fazla

RHEUMATOLOGY, cilt.48, ss.23-25, 2009 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 48 Konu: 1
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1093/rheumatology/ken409
  • Dergi Adı: RHEUMATOLOGY
  • Sayfa Sayıları: ss.23-25

Özet

Objectives. Autoinflammatory diseases constitute a large spectrum of monogenic diseases like FMF or cryopyrin-associated periodic syndromes (CAPS) and complex genetic trait diseases such as systemic onset juvenile idiopathic arthritis (SoJIA). An increased rate of MEFV mutations has been shown among patients with PAN and HSP, in populations where FMF is frequent. The aim of the study is to search for MEFV mutations in our patients with SoJIA and see whether these mutations had an effect on disease course or complications.