MEFV mutations in systemic onset juvenile idiopathic arthritis

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Ayaz N. A., ÖZEN S., BİLGİNER Y., Erguven M., Taskiran E., YILMAZ E., ...Daha Fazla

RHEUMATOLOGY, cilt.48, sa.1, ss.23-25, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 48 Sayı: 1
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1093/rheumatology/ken409
  • Dergi Adı: RHEUMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.23-25
  • Anahtar Kelimeler: Familial Mediterranean fever, Systemic onset juvenile idiopathic arthritis, Mediteranean fever, Mutation, FAMILIAL MEDITERRANEAN FEVER, GENE, PREVALENCE, DISEASE, FREQUENCY, PYRIN, FMF
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Objectives. Autoinflammatory diseases constitute a large spectrum of monogenic diseases like FMF or cryopyrin-associated periodic syndromes (CAPS) and complex genetic trait diseases such as systemic onset juvenile idiopathic arthritis (SoJIA). An increased rate of MEFV mutations has been shown among patients with PAN and HSP, in populations where FMF is frequent. The aim of the study is to search for MEFV mutations in our patients with SoJIA and see whether these mutations had an effect on disease course or complications.