Impact of Oncotype DX Recurrence Score on Treatment Decisions: Results of a Prospective Multicenter Study in Turkey

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Ozmen V., Atasoy A., GÖKMEN E., Ozdogan M., Guler N., URAS C., ...More

CUREUS, vol.8, no.3, 2016 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 8 Issue: 3
  • Publication Date: 2016
  • Doi Number: 10.7759/cureus.522
  • Journal Name: CUREUS
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Directory of Open Access Journals
  • Hacettepe University Affiliated: Yes

Abstract

Introduction: Breast cancer is the most common malignancy among Turkish women and the rate of early stage disease is increasing. The Oncotype DX (R) 21-gene assay is predictive of distant recurrence in ER-positive, HER2-negative early breast cancer. We aimed to evaluate the impact of the Recurrence Score (R) (RS) on treatment decisions and physician perceptions in Turkey. We also studied correlations between RS and routine risk factors.