Serum and gingival crevicular fluid levels of ciprofloxacin in patients with periodontitis

Tozum T. F. , Yildirim A., Caglayan F., Dincel A., Bozkurt A.

JOURNAL OF THE AMERICAN DENTAL ASSOCIATION, vol.135, no.12, pp.1728-1732, 2004 (SCI-Expanded) identifier identifier identifier


Background. The use of antibiotics as an adjunctive therapy in the treatment of periodontal diseases is of special interest to dental practitioners. In addition to using an appropriate antibacterial agent, clinicians may find it useful to determine the local and systemic concentrations of antibiotics in infected periodontal sites to reduce the levels of bacteria. The purpose of this study was to determine the serum and gingival crevicular fluid, or GCF, concentrations of systemic ciprofloxacin in patients with periodontitis.