Role of FDG PET/CT in the Evaluation of Therapy Response in Systemic Juvenile Xanthogranuloma


MAVİ M. E. , Turan B. S. , VOLKAN SALANCI B., BOZKURT M. F.

CLINICAL NUCLEAR MEDICINE, vol.47, no.5, 2022 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Editorial Material
  • Volume: 47 Issue: 5
  • Publication Date: 2022
  • Doi Number: 10.1097/rlu.0000000000004085
  • Journal Name: CLINICAL NUCLEAR MEDICINE
  • Journal Indexes: Science Citation Index Expanded, Scopus, EMBASE, MEDLINE
  • Keywords: systemic juvenile xanthogranuloma, F-18-fluorodeoxyglucose positron emission tomography, FDG PET/CT, therapy response, PATIENT

Abstract

Juvenile xanthogranuloma, a rare type of non-Langerhans cell histiocytosis, is mostly seen in childhood and adolescence and generally manifests as widespread skin lesions. It rarely shows systemic involvement. Although the cutaneous form is often self-limited, systemic form is quite aggressive. Here we report the findings of FDG PET/CT scans during the course of cladribine therapy in a 6-year-old girl with systemic juvenile xanthogranuloma.