Determination of prognosis in patients with prostate cancer treated with radical prostatectomy: Prognostic value of CD44v6 score

Ekici S., Ayhan A., Kendi S., Ozen H.

JOURNAL OF UROLOGY, vol.167, no.5, pp.2037-2041, 2002 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 167 Issue: 5
  • Publication Date: 2002
  • Doi Number: 10.1016/s0022-5347(05)65078-1
  • Journal Name: JOURNAL OF UROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2037-2041
  • Hacettepe University Affiliated: Yes

Abstract

Purpose: A third of the patients treated with radical prostatectomy experience progression even when tumors are confined pathologically to the prostate. CD44 may be a promising prognostic marker for determining malignant potential. However, there has not been a standard scoring system because of its heterogeneous staining pattern. Thus, we developed an objective scoring system to evaluate reliably CD44v6 (Bender Medsystems, Vienna, Austria) as a prognostic marker for prostate cancer.