Analysis of human gingival tissue and gingival crevicular fluid beta-glucuronidase activity in specific periodontal diseases

Layik M., Yamalik N., Caglayan F., Kilinc K., Etikan I., Eratalay K.

JOURNAL OF PERIODONTOLOGY, vol.71, no.4, pp.618-624, 2000 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 71 Issue: 4
  • Publication Date: 2000
  • Doi Number: 10.1902/jop.2000.71.4.618
  • Journal Name: JOURNAL OF PERIODONTOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.618-624
  • Keywords: gingiva, chemistry, gingival crevicular fluid, chemistry, periodontitis, pathophysiology, periodontitis, early-onset, pathophysiology, RAPIDLY PROGRESSIVE PERIODONTITIS, INCREASED INTRACELLULAR LEVELS, ENZYME-ACTIVITY, POLYMORPHONUCLEAR LEUKOCYTES, JUVENILE PERIODONTITIS, ADULT PERIODONTITIS, CLINICAL-PARAMETERS, ATTACHMENT LOSS, RELEASE, INDICATORS
  • Hacettepe University Affiliated: Yes

Abstract

Background: beta -glucuronidase (betaG) is one of the enzymes involved in the destruction of non-collagenous components of the extracellular matrix. It is also considered an indicator or predictor of periodontal disease activity. The present study was conducted to determine the presence and the levels of betaG activity in gingival tissue and gingival crevicular fluid (GCF) in periodontal disease and health status. The validity of 2 expressions of data, total betaG activity versus betaG concentration, and the correlations between clinical periodontal status and betaG profile was also evaluated.