Myelodysplastic syndrome associated with monosomy 7 in a child with Bloom syndrome

Aktas D., Koc A., Boduroglu K., Hicsonmez G., Tuncbilek E.

CANCER GENETICS AND CYTOGENETICS, vol.116, no.1, pp.44-46, 2000 (SCI-Expanded) identifier


Bloom syndrome is a genomic instability syndrome associated with predisposition to development of various types of malignancy. In this report, rye described a 7-year-old boy with Bloom syndrome (BS) and myelodysplastic syndrome (MDS) associated with monosomy 7 and loss of the Y chromosome. To our knowledge, this was the first case with BS showing monosomy 7 and MDS during the early childhood period. (C) 1999 Elsevier Science Inc., 1999. All rights reserved.