Decrease in brain complexity with methylphenidate treatment in boys diagnosed with attention deficit hyperactivity disorder: an entropy-based qEEG analysis


Çetin F. H., Usta M. B., Aydin S., Güven A. S.

29th European Congress of Psychiatry, EPA-2021, 10 - 13 Nisan 2021, ss.633-634, (Özet Bildiri)

  • Yayın Türü: Bildiri / Özet Bildiri
  • Sayfa Sayıları: ss.633-634
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Introduction: Attention deficit hyperactivity (ADHD) disorder is a common childhood neurodevelopmental disorder, and methylphenidate (MPH) is a first-line therapeutic option for treating ADHD. However, how brain complexity and entropy changes with methylphenidate treatment the clinical implications of possible changes in entropy and the clinical implications of possible changes in entropy have yet to be studied. Objectives: This study aimed to reveal how the MPH treatment affects the complexity in the brain of children with ADHD by entropy-based qEEG analysis. In addition, the presence of the relationship between possible neurophysiological changes to be detected with clinical variables and how they are two other important questions of this study to be answered. Methods: During eyes-open resting, EEG signals were recorded from 25 boys with ADHD-combined type before MPH administration and at the end of the 1st month of the treatment.