Clinicopathologic and radiopharmacokinetic factors affecting gamma probe-guided parathyroidectomy.

Ugur, ÖMER; Bozkurt, MURAT; Hamaloglu, ERHAN; Sokmensuer, C; Etikan, İLKER; Ugur, Y; Sayek, I; Gulec, Sa

doi:10.1001/archsurg.139.11.1175

Clinicopathologic and radiopharmacokinetic factors affecting gamma probe-guided parathyroidectomy.

Ugur O., Bozkurt M. F., Hamaloglu E., Sokmensuer C., Etikan I., Ugur Y., ...Daha Fazla

Archives of surgery (Chicago, Ill. : 1960), cilt.139, sa.11, ss.1175-9, 2004 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 139 Sayı: 11
Basım Tarihi: 2004
Doi Numarası: 10.1001/archsurg.139.11.1175
Dergi Adı: Archives of surgery (Chicago, Ill. : 1960)
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1175-9
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Hacettepe Üniversitesi Adresli: Evet

Özet

Hypothesis: The kinetics of technetium Tc 99m sestamibi (MIBI) in primary hyperparathyroidism are variable and affected by the cellular size of the abnormal glands, the parathyroid hormone levels, and the functional expression of P-glycoprotein (Pgp). The success of gamma probe-guided parathyroidectomy is closely related to the parathyroid-to-thyroid activity ratio at the time of surgery. Preoperative determination of maximum uptake ratio may improve the surgical outcome.