A nation-wide survey of patients with homozygous familial hypercholesterolemia phenotype undergoing LDL-apheresis in Turkey (A-HIT 1 registry)

Kayikcioglu, Meral; Tokgozoglu, SADBERK; YILMAZ, MEHMET; KAYNAR, LEYLAGÜL; Aktan, Melih; Durmus, Rana; Gokce, Cumali; Temizhan, Ahmet; ÖZCEBE, OSMAN; KARAAĞAÇ AKYOL, TÜLAY; Okutan, Harika; Sag, Saim; ÖZ GÜL, ÖZEN; Salcioglu, Zafer; Yenercag, Mustafa; Altunkeser, Bulent; KUKU, İRFAN; Yasar, Hamiyet; Kurtoglu, Erdal; Kose, Melis; Demircioglu, Sinan; PEKKOLAY, ZAFER; İLHAN, OSMAN

doi:10.1016/j.atherosclerosis.2018.01.034

A nation-wide survey of patients with homozygous familial hypercholesterolemia phenotype undergoing LDL-apheresis in Turkey (A-HIT 1 registry)

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Kayikcioglu M., Tokgozoglu L., YILMAZ M., KAYNAR L., Aktan M., Durmus R. B., ...More

ATHEROSCLEROSIS, vol.270, pp.42-48, 2018 (SCI-Expanded)

Publication Type: Article / Article
Volume: 270
Publication Date: 2018
Doi Number: 10.1016/j.atherosclerosis.2018.01.034
Journal Name: ATHEROSCLEROSIS
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.42-48
Hacettepe University Affiliated: Yes

Abstract

Background and aims: Homozygous familial hypercholesterolemia (HoFH) is a genetic condition characterized by lethally high levels of low-density lipoprotein cholesterol (LDL-C) from birth, and requires rapid and aggressive intervention to prevent death due to coronary heart disease and/or atherosclerosis. Where available, lipoprotein apheresis (LA) is the mainstay of treatment to promote survival.