Hemolytic uremic syndrome and IgA nephropathy in a child: Coincidence or not?

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Surmeli-Doven S., Delibas A., Gurses I., Kayacan U. R., Coskun-Yilmaz B., Esen K., ...Daha Fazla

TURKISH JOURNAL OF PEDIATRICS, cilt.60, sa.1, ss.81-85, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 60 Sayı: 1
  • Basım Tarihi: 2018
  • Doi Numarası: 10.24953/turkjped.2018.01.012
  • Dergi Adı: TURKISH JOURNAL OF PEDIATRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.81-85
  • Anahtar Kelimeler: Hemolytic uremic syndrome, immunoglobulin A nephropathy, renal failure, glomerulonephritis, childhood, RHABDOMYOLYSIS
  • Hacettepe Üniversitesi Adresli: Evet

Özet

A previously healthy 18-month old boy, presenting with diarrhea, anemia, thrombocytopenia and acute renal failure was admitted to our hospital. Hemolytic uremic syndrome (HUS) was diagnosed with his clinical and laboratory findings. His stool was negative for Shiga toxin producing E. coli (STEC). During follow-up he developed respiratory distress, hypertrophic cardiomyopathy and seizure. His genetic tests for atypical HUS (aHUS) were negative. His clinical and histological findings indicated hemolytic uremic syndrome and immunglobulin A nephropathy (IgAN). The patient responded to steroid treatment and plasma exchange therapy with peritoneal dialysis. We discuss the probable connection between HUS and IgAN.