The role of vascular inflammation markers in deficiency of adenosine deaminase 2

KAYA AKCA Ü., SAĞ E., ÜNAL Ş., KASAP CÜCEOĞLU M., BİLGİNER Y., ÖZEN S.

SEMINARS IN ARTHRITIS AND RHEUMATISM, vol.51, no.4, pp.839-844, 2021 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 51 Issue: 4
  • Publication Date: 2021
  • Doi Number: 10.1016/j.semarthrit.2021.04.013
  • Journal Name: SEMINARS IN ARTHRITIS AND RHEUMATISM
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE
  • Page Numbers: pp.839-844
  • Keywords: Deficiency of adenosine deaminase 2, Vascular inflammation, Biomarker, GLYCATION END-PRODUCTS, POLYARTERITIS-NODOSA, SOLUBLE FORM, SERUM-LEVELS, RECEPTOR, EXPRESSION, BIOMARKERS, DISEASE, STROKE, ALPHA
  • Hacettepe University Affiliated: Yes

Abstract

Objectives: The first objective was to assess the role of vascular inflammatory factors in the pathogenesis of deficiency of adenosine deaminase 2 (DADA2) and to compare these markers among DADA2 patients with different phenotypes. We also aimed to investigate differences between DADA2 patients with vasculitic features and classic polyarteritis nodosa (PAN) for the aforementioned markers.