Minimum prick test panel for adult patients with asthma and rhinitis in Ankara, Turkey


Comert S., DEMİR A. U. , KARAKAYA G. , KALYONCU A. F.

JOURNAL OF ASTHMA, cilt.51, sa.4, ss.417-422, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 51 Konu: 4
  • Basım Tarihi: 2014
  • Doi Numarası: 10.3109/02770903.2013.878846
  • Dergi Adı: JOURNAL OF ASTHMA
  • Sayfa Sayıları: ss.417-422

Özet

Objective: Determination of the number and type of allergens needed to be tested in epidemiological studies is important in order to identify most of the sensitized subjects with a cost-effective approach. This study aimed to investigate the minimum skin prick test panel for the identification of at least 95% of the sensitized subjects with symptoms of asthma and/ or allergic rhinitis (AR) in Ankara, Turkey. Methods: Skin prick test results of 7492 patients who were referred to our outpatient clinic with clinical symptoms of asthma and/ or AR between 1991 and 2005 were evaluated retrospectively. Seven allergens were tested in all and 13 allergens in 4202 patients. The allergen group needed for detection of 95% of the sensitized subjects was determined for both the 7 and 13 allergen panels. The study protocol was approved by the local ethics committee of Hacettepe University. Results: The atopy prevalences in the whole study population and in 4202 patients tested with the 13 allergen panel were calculated as 32.2% and 42.6%, respectively. Three allergens (Phleum pratense, Dermatophagoides pteronyssinus and Artemisia vulgaris) within the 7 allergen panel were adequate for the identification of at least 95% of the sensitized subjects. Olea europae was added to the previous three allergens when the 13 allergen panel was applied. Conclusion: Three to four allergens are sufficient for identification at least 95% of sensitized subjects with asthma and/ or AR in Ankara, Turkey.