An unexpected intracardiac location of yolk sac tumor

Sel K., ALEHAN D., YALÇIN B., ÖNDER S. Ç., AYKAN H. H., Akyuz C., ...Daha Fazla

CARDIOVASCULAR PATHOLOGY, cilt.62, 2023 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 62
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1016/j.carpath.2022.107480
  • Dergi Adı: CARDIOVASCULAR PATHOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Anahtar Kelimeler: Yolk sac tumor, Childhood, Intracardiac tumors, Rhabdomyoma, Alfa feto protein, Germ cell tumors, HEART
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Purpose: In the pediatric population, intracardiac tumors are rare, usually benign, and mostly diagnosed as rhabdomyoma. Yolk sac tumors (YSTs) are a rare malignant type of germ cell tumor that typically occurs in gonads. It can also be seen in midline locations but the intracardiac location is extremely rare.Methods: The case herein comprises an asymptomatic 2.5-year-old girl with a murmur detected under general examination.Results: Echocardiography showed a 3 x 3-cm mass in the right ventricle. Cardiac magnetic resonance imaging revealed a smooth contoured mass in the right ventricle lumen, which was compatible with rhabdomyoma. After surgical resection, the histopathological results showed a YST. This diagnosis was supported by high values of subsequent serum alpha feto-protein. There was no evidence for any other primary location.Conclusion: When an intracardiac mass is observed, a YST should be considered. The increase in the alpha feto-protein level can help in the differential diagnosis.(c) 2022 Elsevier Inc. All rights reserved.