The reduction of extraneural scarring with buccal mucosa graft wrapping around the sciatic nerve: an experimental study in a rat model

BALTU Y., UZUN H., Ozgenel G. Y.

JOURNAL OF PLASTIC SURGERY AND HAND SURGERY, vol.51, no.4, pp.259-263, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 51 Issue: 4
  • Publication Date: 2017
  • Doi Number: 10.1080/2000656x.2016.1241790
  • Journal Name: JOURNAL OF PLASTIC SURGERY AND HAND SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.259-263
  • Keywords: Epineural scar tissue, buccal mucosa graft, nerve adhesion, AMNIOTIC MEMBRANE, REGENERATION, ENHANCEMENT, ADHESIONS, BARRIER, FLAP
  • Hacettepe University Affiliated: Yes

Abstract

Background: The postoperative development of epineural and extraneural scar tissue adversely affects peripheral nerve surgery outcomes. Although several surgical methods, pharmacological agents, and chemical materials have been used to prevent epineural scar formation in both clinical and experimental models, the results are still unsatisfactory. The purpose of this study was to investigate the efficacy of buccal mucosa graft (BMG) wrapping on epineural scarring in an adult rat model.