The reduction of extraneural scarring with buccal mucosa graft wrapping around the sciatic nerve: an experimental study in a rat model

BALTU Y., UZUN H., Ozgenel G. Y.

JOURNAL OF PLASTIC SURGERY AND HAND SURGERY, cilt.51, sa.4, ss.259-263, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 51 Sayı: 4
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1080/2000656x.2016.1241790
  • Dergi Adı: JOURNAL OF PLASTIC SURGERY AND HAND SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.259-263
  • Anahtar Kelimeler: Epineural scar tissue, buccal mucosa graft, nerve adhesion, AMNIOTIC MEMBRANE, REGENERATION, ENHANCEMENT, ADHESIONS, BARRIER, FLAP
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background: The postoperative development of epineural and extraneural scar tissue adversely affects peripheral nerve surgery outcomes. Although several surgical methods, pharmacological agents, and chemical materials have been used to prevent epineural scar formation in both clinical and experimental models, the results are still unsatisfactory. The purpose of this study was to investigate the efficacy of buccal mucosa graft (BMG) wrapping on epineural scarring in an adult rat model.