Comparative effects of vitamin D and methylprednisolone against ischemia/reperfusion injury of rabbit spinal cords


Gurer B., Karakoc A., Bektasoglu P. K. , Kertmen H., Kanat M. A. , Arikok A. T. , ...More

EUROPEAN JOURNAL OF PHARMACOLOGY, vol.813, pp.50-60, 2017 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 813
  • Publication Date: 2017
  • Doi Number: 10.1016/j.ejphar.2017.07.028
  • Journal Name: EUROPEAN JOURNAL OF PHARMACOLOGY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.50-60

Abstract

Introduction: Recent studies have demonstrated the neuroprotective and immunomodulatory effects of 1,25-dihydroxyvitamin D3 (calcitriol), but no previous study has examined these effects on spinal cord ischemia/reperfusion (I/R) injury. Therefore, the present study aimed to evaluate whether calcitriol protects the spinal cord from I/R injury.