Comparative effects of vitamin D and methylprednisolone against ischemia/reperfusion injury of rabbit spinal cords

Gurer, Bora; Karakoc, Abdullah; Bektasoglu, Pinar; Kertmen, Hayri; Kanat, Mehmet; Arikok, Ata; Erguderf, Berrin; SARGON, MUSTAFA; Ozturk, Ozden; Celikoglu, Erhan

doi:10.1016/j.ejphar.2017.07.028

Comparative effects of vitamin D and methylprednisolone against ischemia/reperfusion injury of rabbit spinal cords

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Gurer B., Karakoc A., Bektasoglu P. K., Kertmen H., Kanat M. A., Arikok A. T., ...More

EUROPEAN JOURNAL OF PHARMACOLOGY, vol.813, pp.50-60, 2017 (SCI-Expanded)

Publication Type: Article / Article
Volume: 813
Publication Date: 2017
Doi Number: 10.1016/j.ejphar.2017.07.028
Journal Name: EUROPEAN JOURNAL OF PHARMACOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.50-60
Hacettepe University Affiliated: Yes

Abstract

Introduction: Recent studies have demonstrated the neuroprotective and immunomodulatory effects of 1,25-dihydroxyvitamin D3 (calcitriol), but no previous study has examined these effects on spinal cord ischemia/reperfusion (I/R) injury. Therefore, the present study aimed to evaluate whether calcitriol protects the spinal cord from I/R injury.