Comparative effects of vitamin D and methylprednisolone against ischemia/reperfusion injury of rabbit spinal cords

Gurer, Bora; Karakoc, Abdullah; Bektasoglu, Pinar; Kertmen, Hayri; Kanat, Mehmet; Arikok, Ata; Erguderf, Berrin; SARGON, MUSTAFA; Ozturk, Ozden; Celikoglu, Erhan

doi:10.1016/j.ejphar.2017.07.028

Comparative effects of vitamin D and methylprednisolone against ischemia/reperfusion injury of rabbit spinal cords

Gurer B., Karakoc A., Bektasoglu P. K., Kertmen H., Kanat M. A., Arikok A. T., ...Daha Fazla

EUROPEAN JOURNAL OF PHARMACOLOGY, cilt.813, ss.50-60, 2017 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 813
Basım Tarihi: 2017
Doi Numarası: 10.1016/j.ejphar.2017.07.028
Dergi Adı: EUROPEAN JOURNAL OF PHARMACOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.50-60
Hacettepe Üniversitesi Adresli: Evet

Özet

Introduction: Recent studies have demonstrated the neuroprotective and immunomodulatory effects of 1,25-dihydroxyvitamin D3 (calcitriol), but no previous study has examined these effects on spinal cord ischemia/reperfusion (I/R) injury. Therefore, the present study aimed to evaluate whether calcitriol protects the spinal cord from I/R injury.