Antimicrobial and antimalarial activities of some endemic Turkish Verbascum species

AKDEMİR Z. Ş., Tatli İ. İ., Bedir E., Khan I. A.

Fabad Journal of Pharmaceutical Sciences, vol.28, no.3, pp.131-135, 2004 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 3
  • Publication Date: 2004
  • Journal Name: Fabad Journal of Pharmaceutical Sciences
  • Journal Indexes: Scopus
  • Page Numbers: pp.131-135
  • Hacettepe University Affiliated: Yes


The antimicrobial activities of ethyl acetate and methanol extracts of five Verbascum species were studied. The dried extracts of the aerial parts of Verbascum chionophyllum Hub.-Mor., V. cilicicum Boiss., V. pterocalycinum var. mutense Hub.-Mor., V. pycnostachyum Boiss. & Helder. and V. splendidum Boiss. were tested in vitro against Candida albicans (ATCC 90028), Cryptococcus neoformans (ATCC 90113), Staphylococcus aureus (ATCC 29213), methicillin-resistant S. aureus (ATCC 43300), Pseudomonas aeruginosa (ATCC 27853), Aspergillus fumigatus (ATCC 90906) and Mycobacterium intracellulare (ATCC 23068) using a 96-well microplate assay. Amphotericin B, ciprofloxacin and rifampin were used as positive controls. The antimalarial activities of the same extracts were also tested to Plasmodium falciparum clone [Sierra Leone D6 (chloroquine-sensitive)]. The antimalarial agents chloroquine and artemisinin were used as positive controls. None of the tested extracts showed important antimicrobial or antimalarial activities.