Angiotensin-converting enzyme expression of the lymphoma-associated macrophages in the lymph nodes of Hodgkin's disease

Koca E., Haznedaroglu I. C., ÜNER A., Sayinalp N., Saglam A. E., Goker H., ...More

JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION, vol.99, no.11, pp.1243-1246, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 99 Issue: 11
  • Publication Date: 2007
  • Journal Name: JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1243-1246
  • Hacettepe University Affiliated: Yes

Abstract

Objective: Angiotensin-converting enzyme (ACE) is involved in the control of cellular proliferation. Tumor-associated macrophages promote lymphoma pathogenesis via affecting tumor cell growth and associated survival factors. We assessed ACE expression in the neoplastic lymph node microenvironment of Hodgkin's lymphoma (HL), particularly in macrophages and in nonneoplastic lymphoid tissue.