Angiotensin-converting enzyme expression of the lymphoma-associated macrophages in the lymph nodes of Hodgkin's disease


Koca E., Haznedaroglu I. C. , ÜNER A. , Sayinalp N. , Saglam A. E. , Goker H. , ...Daha Fazla

JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION, cilt.99, sa.11, ss.1243-1246, 2007 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 99 Konu: 11
  • Basım Tarihi: 2007
  • Dergi Adı: JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION
  • Sayfa Sayıları: ss.1243-1246

Özet

Objective: Angiotensin-converting enzyme (ACE) is involved in the control of cellular proliferation. Tumor-associated macrophages promote lymphoma pathogenesis via affecting tumor cell growth and associated survival factors. We assessed ACE expression in the neoplastic lymph node microenvironment of Hodgkin's lymphoma (HL), particularly in macrophages and in nonneoplastic lymphoid tissue.