Long Remission in Muscle-Specific Kinase Antibody-Positive Juvenile Myasthenia
PEDIATRIC NEUROLOGY, cilt.40, sa.6, ss.455-456, 2009 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 40 Sayı: 6
- Basım Tarihi: 2009
- Doi Numarası: 10.1016/j.pediatrneurol.2008.11.014
- Dergi Adı: PEDIATRIC NEUROLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.455-456
- Hacettepe Üniversitesi Adresli: Evet
Özet
The clinical course of anti-muscle specific kinase-positive myasthenia in children has been little reported. Described here is the case of an 8 year-old boy who presented with ptosis and generalized weakness, which resolved within I month without any immunomodulatory treatment. This spontaneous remission lasted 6 years and was then followed by a relapse with bulbar symptoms. The patient was put on plasmapheresis; after initial benefit, symptoms worsened and serum antibody levels persisted. This case constitutes an example of the variability of the clinical presentation, course, and therapeutic response in anti-muscle specific kinase-positive myasthenia in childhood. (C) 2009 by Elsevier Inc. All rights reserved.