In vitro chemosensitivity in ovarian carcinoma: Comparison of three leading assays

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Tatar B., BOYRAZ G., Selcuk I., Dogan A. K., USUBÜTÜN A., TUNCER Z. S.

JOURNAL OF THE TURKISH-GERMAN GYNECOLOGICAL ASSOCIATION, vol.17, no.1, pp.35-40, 2016 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 1
  • Publication Date: 2016
  • Doi Number: 10.5152/jtgga.2016.16017
  • Journal Name: JOURNAL OF THE TURKISH-GERMAN GYNECOLOGICAL ASSOCIATION
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.35-40
  • Keywords: Ovarian cancer, in vitro chemosensitivity, ATP, MTT, DISC, TUMOR CHEMOSENSITIVITY, CHEMORESPONSE ASSAY, CANCER, THERAPY, WOMEN
  • Hacettepe University Affiliated: Yes

Abstract

Objective: An alternative approach to the current therapy of ovarian carcinoma is the individualization of treatment by determining the sensitivity of tumoral tissue to chemotherapeutic agents before the initiation of chemotherapy. The objectives of the study are to determine the efficacy of in vitro chemosensitivity assays in ovarian carcinoma and to measure the correlation of three leading assays.