In vitro chemosensitivity in ovarian carcinoma: Comparison of three leading assays

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Tatar B., BOYRAZ G., Selcuk I., Dogan A. K., USUBÜTÜN A., TUNCER Z. S.

JOURNAL OF THE TURKISH-GERMAN GYNECOLOGICAL ASSOCIATION, cilt.17, sa.1, ss.35-40, 2016 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 1
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5152/jtgga.2016.16017
  • Dergi Adı: JOURNAL OF THE TURKISH-GERMAN GYNECOLOGICAL ASSOCIATION
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.35-40
  • Anahtar Kelimeler: Ovarian cancer, in vitro chemosensitivity, ATP, MTT, DISC, TUMOR CHEMOSENSITIVITY, CHEMORESPONSE ASSAY, CANCER, THERAPY, WOMEN
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Objective: An alternative approach to the current therapy of ovarian carcinoma is the individualization of treatment by determining the sensitivity of tumoral tissue to chemotherapeutic agents before the initiation of chemotherapy. The objectives of the study are to determine the efficacy of in vitro chemosensitivity assays in ovarian carcinoma and to measure the correlation of three leading assays.