Drug Delivery Systems for Imaging and Therapy of Parkinson's Disease
CURRENT NEUROPHARMACOLOGY, vol.14, no.4, pp.376-391, 2016 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 14 Issue: 4
- Publication Date: 2016
- Doi Number: 10.2174/1570159x14666151230124904
- Journal Name: CURRENT NEUROPHARMACOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.376-391
- Open Archive Collection: AVESIS Open Access Collection
- Hacettepe University Affiliated: Yes
Abstract
Background: Although a variety of therapeutic approaches are available for the treatment of Parkinson's disease, challenges limit effective therapy. Among these challenges are delivery of drugs through the blood brain barier to the target brain tissue and the side effects observed during long term administration of antiparkinsonian drugs. The use of drug delivery systems such as liposomes, niosomes, micelles, nanoparticles, nanocapsules, gold nanoparticles, microspheres, microcapsules, nanobubbles, microbubbles and dendrimers is being investigated for diagnosis and therapy.