Drug Delivery Systems for Imaging and Therapy of Parkinson's Disease


GUNAY M. S. , ÖZER A. Y. , CHALON S.

CURRENT NEUROPHARMACOLOGY, cilt.14, ss.376-391, 2016 (SCI İndekslerine Giren Dergi) identifier identifier

Özet

Background: Although a variety of therapeutic approaches are available for the treatment of Parkinson's disease, challenges limit effective therapy. Among these challenges are delivery of drugs through the blood brain barier to the target brain tissue and the side effects observed during long term administration of antiparkinsonian drugs. The use of drug delivery systems such as liposomes, niosomes, micelles, nanoparticles, nanocapsules, gold nanoparticles, microspheres, microcapsules, nanobubbles, microbubbles and dendrimers is being investigated for diagnosis and therapy.