A novel synthetic approach for the synthesis of pyridocarbazole alkaloids

Ergun Y., Patir S., Okay G.

JOURNAL OF HETEROCYCLIC CHEMISTRY, vol.40, no.6, pp.1005-1010, 2003 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 40 Issue: 6
  • Publication Date: 2003
  • Doi Number: 10.1002/jhet.5570400608
  • Journal Name: JOURNAL OF HETEROCYCLIC CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1005-1010
  • Hacettepe University Affiliated: No

Abstract

The synthesis of 11-methyl-6H-pyrido[4,3-b]carbazole-1(2H)-one (5), which can be important for the synthesis of other pyridocarbazole alkaloids and especially 1-substituted ellipticines, is described. Construction of the tetracyclic structure was achieved by a new route and two important precursor compounds (4a and 4b) for the synthesis of pyridocarbazole alkaloids and also many new tetrahydrocarbazole derivatives (7, 8, 9, 10, 11, 12, 13) were synthesized.