Comparison of patients with familial Mediterranean fever accompanied with sacroiliitis and patients with juvenile spondyloarthropathy

Sonmez H. E., Batu E. D., Demir S., Bilginer Y., Ozen S.

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, vol.35, no.6, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 6
  • Publication Date: 2017
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: familial Mediterranean fever, sacroiliitis, juvenile spondyloarthropathy, IDIOPATHIC ARTHRITIS, MEFV MUTATIONS, CHILDREN, DISEASE, CLASSIFICATION, ASSOCIATION, AMYLOIDOSIS, DIAGNOSIS, CRITERIA, GENE
  • Hacettepe University Affiliated: Yes


Objective. Familial Mediterranean fever (FMF) is the most common auto-inflammatory disease manifesting with self-limited recurrent febrile attacks and polyserositis. Acute recurrent monoarthritis is the most common form of musculoskeletal involvement in FMF; however, up to 5% of FMF patients may develop chronic joint diseases including sacroiliitis. It is difficult to distinguish whether sacroiliitis is a musculoskeletal finding of FMF or whether this is the coexistence of two diseases, FMF and SpA. In this study, we aimed to evaluate FMF patients with sacroiliitis, and compare their features with juvenile spondyloarthropathy (SpA) patients, all of whom had sacroiliitis.