Obesity is an important health problem that concerns the whole society including geriatric population. Weight gain by aging or obesity persistance in the old age causes a poor quality life, brings health problems or causes intensity in the existing health matters. Elderly people should be on diet and make physical exercise in order to lose weight. On the other hand, elderly people tend to use herbal preparates more than younger ones. The use herbal preparates and food supplements to solve the overweight problem in old age may cause important toxicological outcomes. In this review the toxicological outcomes of the usage of herbal praparates (ephedra, cafein etc.) food supplements (chromium picollinate, chitosan, etc) in elderly for obesity terapy will be discussed.